Doxorubicin-resistant MCF-7/ADR breast cancer cells
Summary:
Analysis of weakly tumorigenic parental MCF-7 cells and a multistep doxorubicin-selected MCF-7/ADR subline. Results provide insight into whether prolonged continuous selection of cells for drug resistance enriches for cancer stem-like cells.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Calcagno AM, Salcido CD, Gillet JP, Wu CP et al. Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics. J Natl Cancer Inst 2010 Nov 3;102(21):1637-52. PMID: 20935265