Cancer stem cell population in highly metastatic variants of MDA-MB-231 breast cancer cell line
Summary:
Analysis of CD24-/CD44+/ESA+ cancer stem cells from MDA-MB-231 breast cancer (BC) cell line and its highly metastatic variants 231BoM-1833 and 231BrM-2a. The majority of BC deaths are attributed to metastatic disease. Results provide insight into the molecular basis of metastatic progression.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Okuda H, Kobayashi A, Xia B, Watabe M et al. Hyaluronan synthase HAS2 promotes tumor progression in bone by stimulating the interaction of breast cancer stem-like cells with macrophages and stromal cells. Cancer Res 2012 Jan 15;72(2):537-47. PMID: 22113945
