DataSet Record GDS4096: Expression Profiles Data Analysis Tools Sample Subsets
Title: Mutant p53 depletion effect on MDA-468.shp53 breast tumor cell line
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Summary: Analysis of MDA-468.shp53 cells cultured under 3D conditions in the presence of DOX. These cells express a DOX-inducible shRNA targeting endogenous mutant p53. The p53-reduced cells have an invasive, highly disorganized appearance. Results provide insight into role of mutant p53 in breast cancer.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Freed-Pastor WA, Mizuno H, Zhao X, Langerød A et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell 2012 Jan 20;148(1-2):244-58. PMID: 22265415
Reference Series: GSE31812 Sample count: 6
Value type: transformed count Series published: 2012/02/13