Chronic lymphocytic leukemia: peripheral blood B cells (HG-U133A)
Summary:
Analysis of peripheral blood B cells isolated from 41 untreated chronic lymphocytic leukemia (CLL) patients and 11 age-matched control subjects. B-cell CLL is the most common type of leukemia, mainly affecting adults. Results provide insight into molecular mechanisms underlying CLL pathogenesis.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Gutierrez A Jr, Tschumper RC, Wu X, Shanafelt TD et al. LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis. Blood 2010 Oct 21;116(16):2975-83. PMID: 20595513
