Cystic fibrosis transmembrane conductance regulator expression in airway epithelial cells
Summary:
Analysis of Calu-3 airway epithelial cells transfected with miR-138 mimic or SIN3A siRNA. MicroRNA-138 regulates Cystic fibrosis transmembrane conductance regulator (CFTR) expression through its interactions with the transcriptional regulatory protein SIN3A.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Ramachandran S, Karp PH, Jiang P, Ostedgaard LS et al. A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A 2012 Aug 14;109(33):13362-7. PMID: 22853952