Early lung immune response in tuberculosis: time course
Summary:
Analysis of Mycobacterium tuberculosis (Mt)-infected lung 0 to 21 days after infection. TB immunity is associated with IFNγ lung T helper cell type 1 (Th1) accumulation and Mt-infected macrophage activation. Results provide insight into immune events that occur prior to Th1 accumulation in TB lung.
Kang DD, Lin Y, Moreno JR, Randall TD et al. Profiling early lung immune responses in the mouse model of tuberculosis. PLoS One 2011 Jan 13;6(1):e16161. PMID: 21249199