Analysis of composite bone marrow (BM) from healthy children and adults. Normal BM constitutes a complex tissue of blood progenitor cells changing in composition with age. Results provide insight into molecular mechanisms associated with changes in the total precursor B-cell compartment with age.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Jensen K, Schaffer L, Olstad OK, Bechensteen AG et al. Striking decrease in the total precursor B-cell compartment during early childhood as evidenced by flow cytometry and gene expression changes. Pediatr Hematol Oncol 2010 Feb;27(1):31-45. PMID: 20121553
