DataSet Record GDS4287: Expression Profiles Data Analysis Tools Sample Subsets
Title: Effect of Tet2 loss in bone marrow progenitors
Cluster AnalysisGDS4287 Cluster Image
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Summary: Analysis of sorted bone marrow progenitor populations (LSK, CMP, GMP) deficient in ten-eleven translocation 2 (TET2). Tet2 loss causes increased hematopoietic stem cell self-renewal and myeloid transformation. Results provide insight into the molecular mechanisms underlying myeloid malignancies.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011 Jul 12;20(1):11-24. PMID: 21723200
Reference Series: GSE27816 Sample count: 14
Value type: count Series published: 2011/07/01