Analysis of mononuclear cells from PICALM-MLLT10-positive T-cell acute lymphoblastic leukemia (T-ALL) patients (2 cases with histone methyltransferase gene EZH2 mutations) and PICALM-MLLT10-negative T-ALL patients. Results provide insight into molecular mechanisms underlying the leukemia subtypes.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Grossmann V, Bacher U, Kohlmann A, Artusi V et al. EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia. Br J Haematol 2012 May;157(3):387-90. PMID: 22235851