Small molecule KY02111 effect on induced pluripotent stem cell line IMR90-1: time course
Summary:
Analysis of IMR90-1 iPSCs cultured in cardiac differentiation medium containing serum for 3 days, then treated with KY02111 for up to 24 hrs. KY02111 promotes differentiation of PSCs to cardiomyocytes. Results provide insight into molecular basis of KY02111-induced cardiac differentiation of PSCs.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Minami I, Yamada K, Otsuji TG, Yamamoto T et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep 2012 Nov 29;2(5):1448-60. PMID: 23103164