Analysis of endoscopic biopsies of Barrett's esophagus (BE), normal adjacent epithelia gastric cardia, and normal squamous esophagus. BE is a metaplastic condition and precursor to esophageal adenocarcinoma. Results provide insight molecular mechanisms underlying early stages of BE.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
di Pietro M, Lao-Sirieix P, Boyle S, Cassidy A et al. Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus. Proc Natl Acad Sci U S A 2012 Jun 5;109(23):9077-82. PMID: 22603795