High and low chromosomal instability phenotypes in stage II and III colorectal cancers
Summary:
Analysis of specimens from consecutive stage II and stage III colorectal cancer (CRC) patients with high or low chromosomal instability (CIN) phenotype. CIN-high CRC showed poorer outcome than CIN-low CRC. Results provide insight into molecular biomarkers to distinguish between the CIN phenotypes.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Watanabe T, Kobunai T, Yamamoto Y, Matsuda K et al. Chromosomal instability (CIN) phenotype, CIN high or CIN low, predicts survival for colorectal cancer. J Clin Oncol 2012 Jun 20;30(18):2256-64. PMID: 22547595
