Ribavirin effect on uninfected hepatoma Huh7.5.1 cells
Summary:
Analysis of uninfected hepatoma Huh7.5.1 cells treated with ribavirin. In the combination treatment for hepatitis C virus (HCV), ribavirin potentiates the anti-HCV effect of pegylated interferon (PEG-IFN). Results provide insight into the molecular mechanisms underlying ribavirin action.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Thomas E, Feld JJ, Li Q, Hu Z et al. Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models. Hepatology 2011 Jan;53(1):32-41. PMID: 21254160