DataSet Record GDS4400: Expression Profiles Data Analysis Tools Sample Subsets
Title: Fibroblast-derived induced pluripotent stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation
Cluster AnalysisGDS4400 Cluster Image
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Summary: Analysis of IPSCs generated from LRRK2 (Gly2019Ser) mutation-bearing patient fibroblasts by cell reprogramming. The LRRK2 (G2019S) mutation causes familial Parkinson's disease (PD). Results provide insight into the molecular mechanisms underlying PD.
Organism: Homo sapiens
Platform: GPL571: [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
  • Liu GH, Qu J, Suzuki K, Nivet E et al. Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 2012 Nov 22;491(7425):603-7. PMID: 23075850
Reference Series: GSE33298 Sample count: 14
Value type: transformed count Series published: 2012/10/17