DataSet Record GDS4498: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transcription factor Nrf2 gain-of-function model: postnatal day 2.5 whole skin
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Summary: Analysis of whole skin from female, K5cre-caNrf2 transgenics at P2.5. Nrf2 activation induced epidermal thickening and hyperkeratosis resembling human skin disease lamellar ichthyosis. Results provide insight into the role of Nrf2 as a regulator of protective functions of the epidermis.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Schäfer M, Farwanah H, Willrodt AH, Huebner AJ et al. Nrf2 links epidermal barrier function with antioxidant defense. EMBO Mol Med 2012 May;4(5):364-79. PMID: 22383093
Reference Series: GSE35160 Sample count: 6
Value type: count Series published: 2012/02/01