Analysis of right ventricle (RV) from C57BL/6 males subjected to hemoclip installation around the pulmonary artery (PA) for up to 6 weeks. PA clipping induces RV hypertrophy (RVH) while avoiding detrimental RV pressure overload. Results provide insight into the molecular basis of RV remodeling.
Kreymborg Kg, Uchida S, Gellert P, Schneider A et al. Identification of right heart-enriched genes in a murine model of chronic outflow tract obstruction. J Mol Cell Cardiol 2010 Oct;49(4):598-605. PMID: 20673770