Analysis of xpa-1 mutants deficient in nucleotide excision repair (NER). Transcription-blocking DNA damage is believed to contribute to aging and underlie activation of oxidative stress responses (OSR). Results provide insight into the transcriptomic reprogramming response in xpa-1 mutants.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Arczewska KD, Tomazella GG, Lindvall JM, Kassahun H et al. Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1. Nucleic Acids Res 2013 May 1;41(10):5368-81. PMID: 23580547
