Fibroblast response to coculture with basal breast cancer cells
Summary:
Analysis of fibroblasts (HFF1, HFF2, Wi38, CCD1112Sk) and breast cancer epithelial cells (Cal51, MDA-MB-231) FACS-sorted from 6-day cocultures. Cancer-associated fibroblasts can promote tumor formation and growth. Results provide insight into tumor-fibroblast interactions involved in tumorigenicity.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Rajaram M, Li J, Egeblad M, Powers RS. System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. PLoS Genet 2013;9(9):e1003789. PMID: 24068959
