SARM-deficient brain response to vesicular stomatitis virus infection
Summary:
Analysis of brains from SARM-deficient animals infected with the vesicular stomatitis virus (VSV). SARM is a member of the Toll/IL-1R domain-containing adaptor family. VSV is used to study the response to neurotropic viral infections. Results provide insight into the role of SARM in innate immunity.
Hou YJ, Banerjee R, Thomas B, Nathan C et al. SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection. J Immunol 2013 Jul 15;191(2):875-83. PMID: 23749635