Lysyl oxidase-like 2 depletion effect on MDA-MB-231 cells
Summary:
Analysis of MDA-MB-231 cells depleted for Lysyl oxidase-like 2 (LOXL2). LOXL2 is a member of the Lysyl oxidase family of copper-containing enzymes that catalyze the oxidative deamination of epsilon-amino groups in lysines. Results provide insight into the role of LOXL2 in transcriptional regulation.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L et al. Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3. FEBS J 2016 Dec;283(23):4263-4273. PMID: 27735137