Telomere-associated protein Rif1 depletion effect on stem cell lines
Summary:
Analysis of J1 and F1 embryonic stem cells (ESCs) depleted for the telomere-associated protein Rif1. Results provide insight into the role Rif1 in ESC self-renewal and pluripotency.
Dan J, Liu Y, Liu N, Chiourea M et al. Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing. Dev Cell 2014 Apr 14;29(1):7-19. PMID: 24735877
