Streptozotocin effect on pancreas of offspring of protein-restricted dams
Summary:
Analysis of pancreas from streptozotocin-injected female offspring of low protein-fed dams. These offspring fail to regenerate their β-cells following depletion with STZ. Results provide insight into molecular basis of failed β-cell regeneration in offspring of protein-restricted pregnant mice.
Cox AR, Beamish CA, Carter DE, Arany EJ et al. Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice. Exp Biol Med (Maywood) 2013 Oct;238(10):1147-59. PMID: 23986224