Very low density lipoprotein receptor knockout effect in house dust mite model of asthma: lung
Summary:
Analysis of lung from B6129SF2/J animals depleted for very low density lipoprotein receptor (VLDLR) and subjected to intranasal challenge with house dust mite (HDM). VLDLR is a multiligand apolipoprotein E receptor. Results provide insight into the role of VLDLR in HDM-induced airway inflammation.
Fredriksson K, Mishra A, Lam JK, Mushaben EM et al. The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses. J Immunol 2014 May 15;192(10):4497-509. PMID: 24733846
