DataSet Record GDS5008: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transforming growth factor beta deficiency effect on embryonic palatal mesenchymal cells
Cluster AnalysisGDS5008 Cluster Image
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Summary: Analysis of embryonic palatal mesenchyme (PM) cells from mice with a deletion of Tgfbr2 in cranial neural crest cells. These Tgfbr2fl/fl;Wnt1-Cre mice develop cleft palate as the result of abnormal TGFβ signaling activation. Results provide insight into the role of TGFβ in palatogenesis.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Iwata J, Suzuki A, Pelikan RC, Ho TV et al. Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice. Hum Mol Genet 2014 Jan 1;23(1):182-93. PMID: 23975680
Reference Series: GSE46150 Sample count: 8
Value type: transformed count Series published: 2013/10/01