Morbidly obese and non-obese individuals: adipose stem cells
Summary:
Analysis of adipose stem cells (ASC) from subcutaneous white adipose tissue (WAT) of morbidly obese and non-obese individuals. WAT serves as a reservoir for ASCs for cell renewal and repair. Results provide insight into molecular mechanisms by which obesity affects subcutaneous WAT stem cells.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Oñate B, Vilahur G, Camino-López S, Díez-Caballero A et al. Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype. BMC Genomics 2013 Sep 16;14:625. PMID: 24040759
