E2A transcription factor deficiency effect on DN2 thymocyte
Summary:
Analysis of DN2 thymocytes from mutants lacking the transcripton factor E2A. Results provide insight into the role of E2A in the development of T-cells.
Xu W, Carr T, Ramirez K, McGregor S et al. E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment. Blood 2013 Feb 28;121(9):1534-42. PMID: 23297135