Enforced Grainyhead-like 1 expression effect on BE(2)-C neuroblastoma cell line: time course
Summary:
Analysis of BE(2)-C cells up to 72 hrs after transient transfection with construct pTRex-GRHL1. The three mammalian GRHL genes (GRHL1, -2, and -3) represent a highly conserved family of β-scaffold transcription factors. Results provide insight into the role of GRHL1 in neuroblastoma biology.
Fabian J, Lodrini M, Oehme I, Schier MC et al. GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3. Cancer Res 2014 May 1;74(9):2604-16. PMID: 24419085
