Endometrium response to tamoxifen and low dose estradiol combination therapy
Summary:
Analysis of endometria of postmenopausal cynomolgus macaques treated with tamoxifen and low dose estradiol. Tamoxifen is a selective estrogen receptor modulator (SERM). Estrogen and SERM co-therapy is an alternative to estrogen and progestin, a treatment associated with increased breast cancer risk.
Wood CE, Kaplan JR, Fontenot MB, Williams JK et al. Endometrial profile of tamoxifen and low-dose estradiol combination therapy. Clin Cancer Res 2010 Feb 1;16(3):946-56. PMID: 20103679