Analysis of embryonic stem cells from mutants lacking TRPM7. TRPM7 is a kinase and an ion channel. Results provide insight into the function of TRPM7 in cell differentiation and embryonic development.
Krapivinsky G, Krapivinsky L, Manasian Y, Clapham DE. The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase. Cell 2014 May 22;157(5):1061-72. PMID: 24855944