Transcription factor ZNF395 effect on RTS3b skin cancer cell line
Summary:
Analysis of skin cancer cell line RTS3b-TR-ZNF395 following doxycycline-induced expression of FLAG-tagged ZNF395. Transcription factor ZNF395 is overexpressed in various human cancers, often in response to hypoxia. Results provide insight into the molecular effects of ZNF395 in skin cancer cells.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Jordanovski D, Herwartz C, Pawlowski A, Taute S et al. The hypoxia-inducible transcription factor ZNF395 is controlled by IĸB kinase-signaling and activates genes involved in the innate immune response and cancer. PLoS One 2013;8(9):e74911. PMID: 24086395