Fibroblast growth factor 2 effect on lens epithelia explant cultures: time course
Summary:
Analysis of lens explant cultures grown overnight in the presence of 5 ng/mL FGF2 to promote proliferation and survival, then treated with 100 ng/mL FGF2 for up to 24hr to induce differentiation. Results provide insight into the molecular basis of FGF2-induced lens fiber cell differentiation.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Wolf L, Gao CS, Gueta K, Xie Q et al. Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation. G3 (Bethesda) 2013 Dec 9;3(12):2239-55. PMID: 24142921