Listeria monocytogenes infection effect on transcriptional repressor BLIMP1-deficient macrophage
Summary:
Analysis of B lymphocyte-induced maturation protein 1 (BLIMP1) conditional knockout macrophages infected with Listeria monocytogenes for 2 hr. Results provide insight into BLIMP1-mediated regulatory mechanisms in macrophages in early host defense against intracellular bacteria.
Severa M, Islam SA, Waggoner SN, Jiang Z et al. The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8. J Immunol 2014 Mar 1;192(5):2291-304. PMID: 24477914
