Transforming growth factor, beta receptor II knockout effect on embryonic posterior palate
Summary:
Analysis of posterior portions of the palate from E15.5 embryos with an epithelial cell-specific conditional inactivation of Transforming growth factor, beta receptor II (Tgfbr2). Results, together with those from GDS4921, provide insight into the role of TGFβ signaling in soft palate development.
Iwata J, Suzuki A, Yokota T, Ho TV et al. TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate. Development 2014 Feb;141(4):909-17. PMID: 24496627