Hematopoietic stem cell proliferation after 5-fluorouracil treatment: time course
Summary:
Expression profiling of bone marrow Sca+ SP hematopoeitic stem cells (HSC) and fetal liver HSCs of C57BL/6. Bone marrow HSCs examined at various time points up to 30 days after treating mice with 150 mg/kg 5-fluorouracil. Results identify signatures for quiescent and proliferating HSCs.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Venezia TA, Merchant AA, Ramos CA, Whitehouse NL et al. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol 2004 Oct;2(10):e301. PMID: 15459755
