Typical and atypical antipsychotic drugs effect on brain
Summary:
Examination of brains from 13 week ddY males treated for 28 days with an antipsychotic: either the typical drugs chlorpromazine and thioridazine (25 mg/kg each) or the atypical drugs olanzapine (1.25 mg/kg) and quetiapine (18.75 mg/kg). Results provide insight into schizophrenia negative symptoms.
GPL891:
Agilent-011978 Mouse Microarray G4121A (Feature Number version)
Citation:
Iwata S, Morioka H, Miyata A. Classification of antipsychotic drugs by gene expression in the frontal cortex of mice. Nihon Shinkei Seishin Yakurigaku Zasshi 2006 Apr;26(2):107-9. PMID: 16722469
