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    c6ast1 six-cysteine containing astacin protease 1 [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 100049315, updated on 8-Mar-2024

    Summary

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    Gene symbol
    c6ast1
    Gene description
    six-cysteine containing astacin protease 1
    See related
    EnsemblRapid:ENSORLG00000000220
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Also known as
    mnep
    Orthologs
    zebrafish all
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    Genomic context

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    See c6ast1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 3 NC_019861.2 (4553794..4559772, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 3 NC_019861.1 (3148088..3154066, complement)

    Chromosome 3 - NC_019861.2Genomic Context describing neighboring genes Neighboring gene mitochondrial carrier homolog 2 Neighboring gene putative nuclease HARBI1 Neighboring gene astacin like metallo-protease Neighboring gene Fas (tnfrsf6)-associated via death domain

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of teleostean hatching enzyme genes and their paralogous genes. Kawaguchi M, et al. Dev Genes Evol, 2006 Dec. PMID 17016731
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    six-cysteine containing astacin protease 1
    Names
    nephrosin
    NP_001098206.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104736.2 → NP_001098206.1  six-cysteine containing astacin protease 1 precursor

      See identical proteins and their annotated locations for NP_001098206.1

      Status: PROVISIONAL

      Source sequence(s)
      AB256945
      UniProtKB/TrEMBL
      H2L3F6, Q14TH8
      Related
      ENSORLP00000000274.2, ENSORLT00000000274.3
      Conserved Domains (2) summary
      cd04283
      Location:92 → 273
      ZnMc_hatching_enzyme; Zinc-dependent metalloprotease, hatching enzyme-like subfamily. Hatching enzymes are secreted by teleost embryos to digest the egg envelope or chorion. In some teleosts, the hatching enzyme may be a system consisting of two evolutionary related ...
      pfam01400
      Location:86 → 275
      Astacin; Astacin (Peptidase family M12A)

    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019861.2 Reference ASM223467v1 Primary Assembly

      Range
      4553794..4559772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials