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    slk STE20 like kinase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100145483, updated on 4-Nov-2024

    Summary

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    Official Symbol
    slkprovided by Xenbase
    Official Full Name
    STE20 like kinaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-877088
    See related
    Ensembl:ENSXETG00000030054 AllianceGenome:Xenbase:XB-GENE-877088
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    losk; stk2
    Summary
    Predicted to enable ATP binding activity and histone H2AS1 kinase activity. Predicted to act upstream of or within protein phosphorylation. Orthologous to human SLK (STE20 like kinase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slk in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (27904401..27953951, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (19692281..19756810, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene protein kinase C delta type Neighboring gene collagen, type XVII, alpha 1 Neighboring gene STN1, CST complex subunit Neighboring gene uncharacterized LOC108645429

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    STE20-like serine/threonine-protein kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      27904401..27953951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031906450.1 → XP_031762310.1  STE20-like serine/threonine-protein kinase isoform X2

      UniProtKB/TrEMBL
      A0A6I8STF3, A0A8J1JZ76
      Related
      ENSXETP00000063709.3, ENSXETT00000062775.3
      Conserved Domains (2) summary
      cd06643
      Location:28 → 310
      STKc_SLK; Catalytic domain of the Serine/Threonine Kinase, Ste20-Like Kinase
      pfam12474
      Location:1105 → 1245
      PKK; Polo kinase kinase

    2. XM_031906451.1 → XP_031762311.1  STE20-like serine/threonine-protein kinase isoform X3

      UniProtKB/TrEMBL
      A0A6I8QZE3, A0A6I8S5L0
      Related
      ENSXETP00000074469.2, ENSXETT00000094047.2
      Conserved Domains (2) summary
      cd06643
      Location:28 → 310
      STKc_SLK; Catalytic domain of the Serine/Threonine Kinase, Ste20-Like Kinase
      pfam12474
      Location:1092 → 1232
      PKK; Polo kinase kinase

    3. XM_031906449.1 → XP_031762309.1  STE20-like serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A6I8S5L0, A0A6I8SG89
      Related
      ENSXETP00000096151.2, ENSXETT00000088261.2
      Conserved Domains (2) summary
      cd06643
      Location:28 → 310
      STKc_SLK; Catalytic domain of the Serine/Threonine Kinase, Ste20-Like Kinase
      pfam12474
      Location:1123 → 1263
      PKK; Polo kinase kinase
    Nucleotide Protein Strain
    Heading Accession and Version

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