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    PRDX3 peroxiredoxin 3 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100174238, updated on 26-Mar-2024

    Summary

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    Gene symbol
    PRDX3
    Gene description
    peroxiredoxin 3
    Locus tag
    CR201_G0012746
    See related
    Ensembl:ENSPPYG00000002700
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    See PRDX3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 8 NC_071993.2 (126221503..126232500, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 10 NC_071995.1 (122425296..122436295, complement)

    Chromosome 8 - NC_071993.2Genomic Context describing neighboring genes Neighboring gene DENN domain containing 10 Neighboring gene sideroflexin 4 Neighboring gene G protein-coupled receptor kinase 5 Neighboring gene uncharacterized LOC134762021 Neighboring gene uncharacterized LOC129048367

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp468N2116

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hydrogen peroxide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin-dependent peroxide reductase, mitochondrial
    Names
    thioredoxin-dependent peroxiredoxin 3
    NP_001127184.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001133712.2 → NP_001127184.1  thioredoxin-dependent peroxide reductase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001127184.1

      Status: PROVISIONAL

      Source sequence(s)
      CR857380
      UniProtKB/Swiss-Prot
      Q5REY3
      UniProtKB/TrEMBL
      A0A2J8W6R9, A0A8I5UH31
      Related
      ENSPPYP00000003152.2, ENSPPYT00000003258.3
      Conserved Domains (1) summary
      cd03015
      Location:65 → 236
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071993.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      126221503..126232500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5REY3.1 GenPept UniProtKB/Swiss-Prot:Q5REY3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials