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    ptch2.L patched 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100191013, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ptch2.L
    Official Full Name
    patched 2 L homeolog
    Primary source
    Xenbase:XB-GENE-1033872
    Locus tag
    XELAEV_18023085mg
    See related
    EnsemblRapid:ENSXLAG00005031482
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ptc2; ptc-2; ptch2; xptc-2; ptch2-a; ptch2-b; Xptch-2'; patched-2
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    Genomic context

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    See ptch2.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (85712289..85741083)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (80415071..80443918)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108714273 Neighboring gene eukaryotic translation initiation factor 2B subunit gamma L homeolog Neighboring gene BTB/POZ domain-containing protein 19-like Neighboring gene uncharacterized LOC121403048 Neighboring gene polo-like kinase 3 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development. Takabatake T, et al. Mech Dev, 2000 Nov. PMID 11044611
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC79874

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables hedgehog family protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hedgehog receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables smoothened binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    patched 2 L homeolog
    Names
    patched homolog 2
    xptc 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136166.1 → NP_001129638.1  patched 2 L homeolog

      See identical proteins and their annotated locations for NP_001129638.1

      Status: PROVISIONAL

      Source sequence(s)
      BC070995
      UniProtKB/TrEMBL
      A0A974D5D7, Q6IRA5
      Related
      ENSXLAP00005094451.1, ENSXLAT00005096153.1
      Conserved Domains (2) summary
      TIGR00918
      Location:26 → 1172
      2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family
      pfam12349
      Location:443 → 593
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      85712289..85741083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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