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    CNTF ciliary neurotrophic factor [ Sarcophilus harrisii (Tasmanian devil) ]

    Gene ID: 100918670, updated on 8-Mar-2024

    Summary

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    Gene symbol
    CNTF
    Gene description
    ciliary neurotrophic factor
    See related
    Ensembl:ENSSHAG00000027930
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sarcophilus harrisii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
    Orthologs
    human mouse all
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    Genomic context

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    See CNTF in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current mSarHar1.11 (GCF_902635505.1) 6 NC_045431.1 (247587114..247591614, complement)
    102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 6 Unlocalized Scaffold NW_003846911.1 (250270..252997)

    Chromosome 6 - NC_045431.1Genomic Context describing neighboring genes Neighboring gene glycine N-acyltransferase-like protein 2 Neighboring gene glycine N-acyltransferase Neighboring gene ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Neighboring gene leupaxin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ciliary neurotrophic factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in astrocyte activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ciliary neurotrophic factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axon regeneration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ciliary neurotrophic factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mSarHar1.11 Primary Assembly

    Genomic

    1. NC_045431.1 Reference mSarHar1.11 Primary Assembly

      Range
      247587114..247591614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003773988.4 → XP_003774036.1  ciliary neurotrophic factor

      UniProtKB/TrEMBL
      A0A7N4P4Q4
      Related
      ENSSHAP00000032320.1, ENSSHAT00000035319.1
      Conserved Domains (1) summary
      pfam01110
      Location:1 → 188
      CNTF; Ciliary neurotrophic factor
    Nucleotide Protein
    Heading Accession and Version

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