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    HCK HCK proto-oncogene, Src family tyrosine kinase [ Papio anubis (olive baboon) ]

    Gene ID: 101016095, updated on 11-Apr-2024

    Summary

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    Gene symbol
    HCK
    Gene description
    HCK proto-oncogene, Src family tyrosine kinase
    See related
    Ensembl:ENSPANG00000016045
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Papio anubis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
    Orthologs
    human mouse all
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    Genomic context

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    See HCK in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    104 current Panubis1.0 (GCF_008728515.1) 16 NC_044991.1 (59185949..59234868)
    103 previous assembly Panu_3.0 (GCF_000264685.3) 10 NC_018161.2 (32203699..32253588, complement)

    Chromosome 16 - NC_044991.1Genomic Context describing neighboring genes Neighboring gene XK related 7 Neighboring gene uncharacterized LOC103888056 Neighboring gene CCM2 like scaffold protein Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene probable ribosome biogenesis protein RLP24 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase HCK
    Names
    hemopoietic cell kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Panubis1.0 Primary Assembly

    Genomic

    1. NC_044991.1 Reference Panubis1.0 Primary Assembly

      Range
      59185949..59234868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003904891.4 → XP_003904940.1  tyrosine-protein kinase HCK isoform X1

      UniProtKB/TrEMBL
      A0A096NUZ0
      Related
      ENSPANP00000016865.2, ENSPANT00000023797.3
      Conserved Domains (3) summary
      cd10363
      Location:118 → 221
      SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
      cl17036
      Location:60 → 115
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:232 → 502
      PKc_like; Protein Kinases, catalytic domain

    2. XM_021921159.2 → XP_021776851.1  tyrosine-protein kinase HCK isoform X1

      UniProtKB/TrEMBL
      A0A096NUZ0
      Conserved Domains (3) summary
      cd10363
      Location:118 → 221
      SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
      cl17036
      Location:60 → 115
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:232 → 502
      PKc_like; Protein Kinases, catalytic domain

    3. XM_031656649.1 → XP_031512509.1  tyrosine-protein kinase HCK isoform X3

      UniProtKB/TrEMBL
      A0A096NUZ0
      Conserved Domains (3) summary
      cd10363
      Location:118 → 221
      SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
      cl17036
      Location:60 → 115
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:232 → 442
      PKc_like; Protein Kinases, catalytic domain

    4. XM_021921160.2 → XP_021776852.1  tyrosine-protein kinase HCK isoform X2

      UniProtKB/TrEMBL
      A0A096NUZ0
      Conserved Domains (3) summary
      cl15255
      Location:118 → 205
      SH2; Src homology 2 (SH2) domain
      cl17036
      Location:60 → 115
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:208 → 451
      PKc_like; Protein Kinases, catalytic domain

    5. XM_031656651.1 → XP_031512511.1  tyrosine-protein kinase HCK isoform X4

      UniProtKB/TrEMBL
      A0A096NUZ0
      Conserved Domains (3) summary
      cd10363
      Location:36 → 139
      SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
      cl17036
      Location:1 → 33
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:150 → 420
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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