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    ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 [ Gorilla gorilla gorilla (western lowland gorilla) ]

    Gene ID: 101129382, updated on 10-Oct-2024

    Summary

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    Gene symbol
    ARIH2
    Gene description
    ariadne RBR E3 ubiquitin protein ligase 2
    See related
    Ensembl:ENSGGOG00000017134
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gorilla gorilla gorilla (sub-species: gorilla)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
    Orthologs
    human mouse all
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    Genomic context

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    See ARIH2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 2 NC_086017.1 (58787269..58853246)
    RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 3 NC_073227.1 (58892681..58958650)

    Chromosome 2 - NC_086017.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109026361 Neighboring gene solute carrier family 25 member 20 Neighboring gene ariadne RBR E3 ubiquitin protein ligase 2 opposite strand Neighboring gene uncharacterized LOC134758052 Neighboring gene uncharacterized LOC129532566 Neighboring gene prolyl 4-hydroxylase, transmembrane Neighboring gene WD repeat domain 6 Neighboring gene DALR anticodon binding domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase ARIH2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Genomic

    1. NC_086017.1 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

      Range
      58787269..58853246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_055382420.1 → XP_055238395.1  E3 ubiquitin-protein ligase ARIH2 isoform X8

    2. XM_055382419.1 → XP_055238394.1  E3 ubiquitin-protein ligase ARIH2 isoform X7

    3. XM_063703787.1 → XP_063559857.1  E3 ubiquitin-protein ligase ARIH2 isoform X1

    4. XM_063703789.1 → XP_063559859.1  E3 ubiquitin-protein ligase ARIH2 isoform X2

      UniProtKB/TrEMBL
      G3SDP4

    5. XM_055382412.2 → XP_055238387.1  E3 ubiquitin-protein ligase ARIH2 isoform X1

    6. XM_055382416.2 → XP_055238391.1  E3 ubiquitin-protein ligase ARIH2 isoform X3

    7. XM_063703788.1 → XP_063559858.1  E3 ubiquitin-protein ligase ARIH2 isoform X1

    8. XM_055382414.2 → XP_055238389.1  E3 ubiquitin-protein ligase ARIH2 isoform X2

      UniProtKB/TrEMBL
      G3SDP4

    9. XM_031009583.3 → XP_030865443.1  E3 ubiquitin-protein ligase ARIH2 isoform X3

      UniProtKB/TrEMBL
      A0A2I2Z884
      Conserved Domains (2) summary
      smart00647
      Location:136 → 198
      IBR; In Between Ring fingers
      cd16773
      Location:65 → 118
      RING-HC_RBR_TRIAD1; RING finger, HC subclass, found in two RING fingers and DRIL [double RING finger linked] 1 (TRIAD1)

    10. XM_055382417.1 → XP_055238392.1  E3 ubiquitin-protein ligase ARIH2 isoform X4

    11. XM_063703790.1 → XP_063559860.1  E3 ubiquitin-protein ligase ARIH2 isoform X6

    12. XM_055382415.1 → XP_055238390.1  E3 ubiquitin-protein ligase ARIH2 isoform X3

    13. XM_055382418.1 → XP_055238393.1  E3 ubiquitin-protein ligase ARIH2 isoform X5

    Nucleotide Protein
    Heading Accession and Version

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