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    LOC101832694 DNA dC->dU-editing enzyme APOBEC-3 [ Mesocricetus auratus (golden hamster) ]

    Gene ID: 101832694, updated on 19-Jun-2024

    Summary

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    Gene symbol
    LOC101832694
    Gene description
    DNA dC->dU-editing enzyme APOBEC-3
    See related
    EnsemblRapid:ENSMAUG00000011683
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mesocricetus auratus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
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    Genomic context

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    See LOC101832694 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429194.1 (84942088..84956510, complement)
    102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801613.1 (2161262..2175047)

    NW_024429194.1Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor subunit B Neighboring gene chromobox 7 Neighboring gene chromobox 6 Neighboring gene neuronal pentraxin receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Ying B, et al. Virology, 2015 Nov. PMID 26319212, Free PMC Article
    2. De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. McCann KE, et al. Sci Rep, 2017 Jan 10. PMID 28071753, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytidine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA cytosine deamination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytidine to uridine editing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA dC->dU-editing enzyme APOBEC-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference BCM_Maur_2.0 Primary Assembly

    Genomic

    1. NW_024429194.1 Reference BCM_Maur_2.0 Primary Assembly

      Range
      84942088..84956510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013111124.3 → XP_012966578.1  DNA dC->dU-editing enzyme APOBEC-3 isoform X1

      UniProtKB/TrEMBL
      A0A1U8BSR7
      Related
      ENSMAUP00000046213.1, ENSMAUT00000036394.1
      Conserved Domains (3) summary
      cd01283
      Location:239 → 337
      cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
      pfam05240
      Location:153 → 197
      APOBEC_C; APOBEC-like C-terminal domain
      pfam08210
      Location:40 → 208
      APOBEC_N; APOBEC-like N-terminal domain

    2. XM_040754127.1 → XP_040610061.1  DNA dC->dU-editing enzyme APOBEC-3 isoform X2

      Conserved Domains (2) summary
      cd01283
      Location:138 → 236
      cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
      cl00269
      Location:5 → 55
      cytidine_deaminase-like; Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes. All members ...
    Nucleotide Protein Strain
    Heading Accession and Version

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