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    NAIP NLR family apoptosis inhibitory protein [ Myotis brandtii (Brandt's bat) ]

    Gene ID: 102249569, updated on 19-Jun-2024

    Summary

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    Gene symbol
    NAIP
    Gene description
    NLR family apoptosis inhibitory protein
    Locus tag
    D623_10035902
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis brandtii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human all
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    Genomic context

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    See NAIP in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    101 current ASM41265v1 (GCF_000412655.1) Unplaced Scaffold NW_005353967.1 (14120836..14168490)

    NW_005353967.1Genomic Context describing neighboring genes Neighboring gene occludin Neighboring gene uncharacterized LOC102248681 Neighboring gene general transcription factor IIH subunit 2 Neighboring gene small EDRK-rich factor 1 Neighboring gene survival of motor neuron 1, telomeric Neighboring gene BDP1 general transcription factor IIIB subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_005353967.1 Unplaced Scaffold Reference ASM41265v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pyroptotic inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of IPAF inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    baculoviral IAP repeat-containing protein 1
    Names
    Baculoviral IAP repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis brandtii Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM41265v1

    Genomic

    1. NW_005353967.1 Reference ASM41265v1

      Range
      14120836..14168490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005857997.2 → XP_005858059.2  baculoviral IAP repeat-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      S7ME52
      Conserved Domains (8) summary
      smart00238
      Location:221 → 291
      BIR; Baculoviral inhibition of apoptosis protein repeat
      smart00382
      Location:525 → 652
      AAA; ATPases associated with a variety of cellular activities
      COG4886
      Location:1132 → 1305
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00022
      Location:123 → 191
      BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
      cd00116
      Location:1190 → 1391
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:1142 → 1166
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:1193 → 1218
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:526 → 680
      NACHT; NACHT domain

    2. XM_014549458.1 → XP_014404944.1  baculoviral IAP repeat-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      S7ME52
      Conserved Domains (8) summary
      smart00238
      Location:159 → 229
      BIR; Baculoviral inhibition of apoptosis protein repeat
      smart00382
      Location:463 → 590
      AAA; ATPases associated with a variety of cellular activities
      COG4886
      Location:1070 → 1243
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00022
      Location:61 → 129
      BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
      cd00116
      Location:1128 → 1329
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:1080 → 1104
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:1131 → 1156
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:464 → 618
      NACHT; NACHT domain

    3. XM_014549465.1 → XP_014404951.1  baculoviral IAP repeat-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      S7ME52
      Conserved Domains (8) summary
      smart00238
      Location:159 → 229
      BIR; Baculoviral inhibition of apoptosis protein repeat
      smart00382
      Location:463 → 590
      AAA; ATPases associated with a variety of cellular activities
      COG4886
      Location:1070 → 1243
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00022
      Location:61 → 129
      BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
      cd00116
      Location:1128 → 1329
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:1080 → 1104
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:1131 → 1156
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:464 → 618
      NACHT; NACHT domain
    Nucleotide Protein
    Heading Accession and Version

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