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    NOTCH1 notch receptor 1 [ Calypte anna (Anna's hummingbird) ]

    Gene ID: 103531621, updated on 3-Aug-2024

    Summary

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    Gene symbol
    NOTCH1
    Gene description
    notch receptor 1
    Locus tag
    N300_08786
    See related
    EnsemblRapid:ENSCAAG00010011627
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Calypte anna
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Strisores; Apodiformes; Trochilidae; Calypte
    Orthologs
    human mouse all
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    Genomic context

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    See NOTCH1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    101 current bCalAnn1_v1.p (GCF_003957555.1) 17 NC_044262.1 (9875906..9917390)
    100 previous assembly ASM69908v1 (GCF_000699085.1) Unplaced Scaffold NW_007620685.1 (580812..605474, complement)

    Chromosome 17 - NC_044262.1Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene EGF like domain multiple 7 Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor Neighboring gene small nuclear RNA activating complex polypeptide 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Notch binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of developmental process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neurogenic locus notch homolog protein 1
    Names
    Neurogenic locus notch protein 1
    notch 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Calypte anna Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bCalAnn1_v1.p

    Genomic

    1. NC_044262.1 Reference bCalAnn1_v1.p

      Range
      9875906..9917390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030461205.1 → XP_030317065.1  neurogenic locus notch homolog protein 1 isoform X1

      Related
      ENSCAAP00010016098.1, ENSCAAT00010017040.1
      Conserved Domains (9) summary
      smart00004
      Location:1442 → 1479
      NL; Domain found in Notch and Lin-12
      COG0666
      Location:1930 → 2125
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00054
      Location:945 → 981
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00045
      Location:1879 → 1924
      ANK; ANK repeat [structural motif]
      pfam00066
      Location:1488 → 1522
      Notch; LNR domain
      pfam03154
      Location:2154 → 2546
      Atrophin-1; Atrophin-1 family
      pfam06816
      Location:1565 → 1617
      NOD; NOTCH protein
      pfam07684
      Location:1670 → 1723
      NODP; NOTCH protein
      pfam11936
      Location:2478 → 2539
      DUF3454; Domain of unknown function (DUF3454)

    2. XM_030461206.1 → XP_030317066.1  neurogenic locus notch homolog protein 1 isoform X2

      Conserved Domains (9) summary
      smart00004
      Location:1396 → 1433
      NL; Domain found in Notch and Lin-12
      COG0666
      Location:1884 → 2079
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00054
      Location:945 → 981
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00045
      Location:1833 → 1878
      ANK; ANK repeat [structural motif]
      pfam00066
      Location:1442 → 1476
      Notch; LNR domain
      pfam03154
      Location:2108 → 2500
      Atrophin-1; Atrophin-1 family
      pfam06816
      Location:1519 → 1571
      NOD; NOTCH protein
      pfam07684
      Location:1624 → 1677
      NODP; NOTCH protein
      pfam11936
      Location:2432 → 2493
      DUF3454; Domain of unknown function (DUF3454)
    Nucleotide Protein
    Heading Accession and Version

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