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    CHN2 chimerin 2 [ Merops nubicus (carmine bee-eater) ]

    Gene ID: 103779517, updated on 3-Aug-2024

    Summary

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    Gene symbol
    CHN2
    Gene description
    chimerin 2
    Locus tag
    N331_11930
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Merops nubicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Coraciimorphae; Coraciiformes; Meropidae; Merops
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    100 current ASM69184v1 (GCF_000691845.1) Unplaced Scaffold NW_008630080.1 (4368..30966, complement)

    NW_008630080.1Genomic Context describing neighboring genes

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_008630080.1 Unplaced Scaffold Reference ASM69184v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-chimaerin
    Names
    Beta-chimaerin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Merops nubicus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM69184v1

    Genomic

    1. NW_008630080.1 Reference ASM69184v1

      Range
      4368..30966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008947143.1 → XP_008945391.1  beta-chimaerin isoform X1

      Conserved Domains (2) summary
      cd04372
      Location:203 → 396
      RhoGAP_chimaerin; RhoGAP_chimaerin: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two ...
      pfam00130
      Location:143 → 195
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

    2. XM_008947145.1 → XP_008945393.1  beta-chimaerin isoform X3

      See identical proteins and their annotated locations for XP_008945393.1

      Conserved Domains (2) summary
      pfam00130
      Location:128 → 180
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      cl02570
      Location:188 → 309
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    3. XM_008947144.1 → XP_008945392.1  beta-chimaerin isoform X2

      See identical proteins and their annotated locations for XP_008945392.1

      Conserved Domains (2) summary
      pfam00130
      Location:128 → 180
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      cl02570
      Location:188 → 335
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    4. XM_008947149.1 → XP_008945397.1  beta-chimaerin isoform X7

      See identical proteins and their annotated locations for XP_008945397.1

      Conserved Domains (2) summary
      pfam00130
      Location:79 → 110
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      cl02570
      Location:107 → 228
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    5. XM_008947147.1 → XP_008945395.1  beta-chimaerin isoform X5

      See identical proteins and their annotated locations for XP_008945395.1

      Conserved Domains (2) summary
      pfam00130
      Location:79 → 110
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      cl02570
      Location:107 → 274
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    6. XM_008947148.1 → XP_008945396.1  beta-chimaerin isoform X6

      See identical proteins and their annotated locations for XP_008945396.1

      Conserved Domains (2) summary
      pfam00130
      Location:37 → 86
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      cl02570
      Location:94 → 241
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    7. XM_008947146.1 → XP_008945394.1  beta-chimaerin isoform X4

      See identical proteins and their annotated locations for XP_008945394.1

      Conserved Domains (2) summary
      cd04372
      Location:94 → 287
      RhoGAP_chimaerin; RhoGAP_chimaerin: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two ...
      pfam00130
      Location:37 → 86
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    Nucleotide Protein
    Heading Accession and Version

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