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    LOC105436672 serine/threonine-protein kinase mTOR [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 105436672, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC105436672
    Gene description
    serine/threonine-protein kinase mTOR
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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    Genomic context

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    See LOC105436672 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145601.1 (23651268..23669611)

    NW_022145601.1Genomic Context describing neighboring genes Neighboring gene mechanistic target of rapamycin kinase Neighboring gene collagen alpha-2(VIII) chain Neighboring gene leucine-rich repeat-containing protein 4-like Neighboring gene G-protein coupled receptor GRL101

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022145601 Unplaced Scaffold Reference Spur_5.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-containing complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TOR signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TORC1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of TORC2 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase mTOR

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145601.1 Reference Spur_5.0 Primary Assembly

      Range
      23651268..23669611
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030987083.1 → XP_030842943.1  serine/threonine-protein kinase mTOR isoform X1

      UniProtKB/TrEMBL
      A0A7M7SZJ7
      Conserved Domains (3) summary
      cd05169
      Location:156 → 434
      PIKKc_TOR; Catalytic domain of Target of Rapamycin
      pfam02260
      Location:521 → 552
      FATC; FATC domain
      pfam08771
      Location:18 → 115
      FRB_dom; FKBP12-rapamycin binding domain

    2. XM_011662483.2 → XP_011660785.2  serine/threonine-protein kinase mTOR isoform X2

      UniProtKB/TrEMBL
      A0A7M7LVH8
      Conserved Domains (3) summary
      cd05169
      Location:156 → 434
      PIKKc_TOR; Catalytic domain of Target of Rapamycin
      pfam02260
      Location:519 → 550
      FATC; FATC domain
      pfam08771
      Location:18 → 115
      FRB_dom; FKBP12-rapamycin binding domain

    3. XM_030987084.1 → XP_030842944.1  serine/threonine-protein kinase mTOR isoform X3

      UniProtKB/TrEMBL
      A0A7M7NXD5
      Conserved Domains (3) summary
      cd05169
      Location:156 → 434
      PIKKc_TOR; Catalytic domain of Target of Rapamycin
      pfam02260
      Location:517 → 548
      FATC; FATC domain
      pfam08771
      Location:18 → 115
      FRB_dom; FKBP12-rapamycin binding domain
    Nucleotide Protein
    Heading Accession and Version

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