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    HIPK2 homeodomain interacting protein kinase 2 [ Acinonyx jubatus (cheetah) ]

    Gene ID: 106970433, updated on 13-Mar-2024

    Summary

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    Gene symbol
    HIPK2
    Gene description
    homeodomain interacting protein kinase 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Acinonyx jubatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
    Orthologs
    human mouse all
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    Genomic context

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    See HIPK2 in Genome Data Viewer
    Location:
    chromosome: A2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) A2 NC_069383.1 (14666174..14846453)

    Chromosome A2 - NC_069383.1Genomic Context describing neighboring genes Neighboring gene poly(ADP-ribose) polymerase family member 12 Neighboring gene uncharacterized LOC113604175 Neighboring gene thromboxane A synthase 1 Neighboring gene uncharacterized LOC128314701 Neighboring gene uncharacterized LOC128314702 Neighboring gene uncharacterized LOC113604174 Neighboring gene uncharacterized LOC128314703 Neighboring gene C-type lectin domain family 2 member L

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_069383.1 Chromosome A2 Reference VMU_Ajub_asm_v1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeodomain-interacting protein kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference VMU_Ajub_asm_v1.0

    Genomic

    1. NC_069383.1 Reference VMU_Ajub_asm_v1.0

      Range
      14666174..14846453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_053218009.1 → XP_053073984.1  homeodomain-interacting protein kinase 2 isoform X4

    2. XM_053218008.1 → XP_053073983.1  homeodomain-interacting protein kinase 2 isoform X2

    3. XM_027075587.2 → XP_026931388.1  homeodomain-interacting protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A6J2APZ0
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    4. XM_027075588.2 → XP_026931389.1  homeodomain-interacting protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A6J2AS60
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    5. XM_053218011.1 → XP_053073986.1  homeodomain-interacting protein kinase 2 isoform X8

    6. XM_053218010.1 → XP_053073985.1  homeodomain-interacting protein kinase 2 isoform X7

    7. XM_027075589.2 → XP_026931390.1  homeodomain-interacting protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A6J2ASM8
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    8. XM_027075590.2 → XP_026931391.1  homeodomain-interacting protein kinase 2 isoform X6

      UniProtKB/TrEMBL
      A0A6J2ANH0
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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