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    KDR kinase insert domain receptor [ Coturnix japonica (Japanese quail) ]

    Gene ID: 107313758, updated on 14-Mar-2024

    Summary

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    Gene symbol
    KDR
    Gene description
    kinase insert domain receptor
    See related
    Ensembl:ENSCJPG00005010680
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Coturnix japonica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Perdicinae; Coturnix
    Also known as
    EK1; FLK-1; Quek1; VEGFR-2
    Orthologs
    human mouse all
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    Genomic context

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    See KDR in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    101 current Coturnix japonica 2.1 (GCF_001577835.2) 4 NC_029519.1 (58803936..58831351)

    Chromosome 4 - NC_029519.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 165 Neighboring gene steroid 5 alpha-reductase 3 Neighboring gene KIT proto-oncogene, receptor tyrosine kinase Neighboring gene platelet derived growth factor receptor alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_029519.1 Chromosome 4 Reference Coturnix japonica 2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules. Eichmann A, et al. Gene, 1996 Sep 26. PMID 8863722
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables vascular endothelial growth factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endothelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vascular endothelial growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vascular endothelial growth factor receptor 2
    Names
    Endothelial kinase receptor EK1
    Quek 1
    Vascular endothelial growth factor receptor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Coturnix japonica Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Coturnix japonica 2.1 Primary Assembly

    Genomic

    1. NC_029519.1 Reference Coturnix japonica 2.1 Primary Assembly

      Range
      58803936..58831351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015862341.2 → XP_015717827.1  vascular endothelial growth factor receptor 2

      UniProtKB/Swiss-Prot
      P52583
      UniProtKB/TrEMBL
      A0A8C2TEI5
      Related
      ENSCJPP00005012560.1, ENSCJPT00005018175.1
      Conserved Domains (7) summary
      cd05862
      Location:234 → 318
      Ig1_VEGFR; First immunoglobulin (Ig)-like domain of vascular endothelial growth factor (VEGF) receptor(R)
      cd05864
      Location:339 → 408
      Ig2_VEGFR-2; Second immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 2 (VEGFR-2)
      smart00408
      Location:671 → 735
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:330 → 408
      IG_like; Immunoglobulin like
      pfam07679
      Location:658 → 745
      I-set; Immunoglobulin I-set domain
      cd05103
      Location:817 → 1160
      PTKc_VEGFR2; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 2
      pfam07714
      Location:825 → 1153
      Pkinase_Tyr; Protein tyrosine kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P52583.1 GenPept UniProtKB/Swiss-Prot:P52583

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