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    dclk1.S doublecortin like kinase 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108709942, updated on 4-Nov-2024

    Summary

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    Official Symbol
    dclk1.S
    Official Full Name
    doublecortin like kinase 1 S homeolog
    Primary source
    Xenbase:XB-GENE-17333490
    Locus tag
    XELAEV_18016161mg
    See related
    EnsemblRapid:ENSXLAG00005021289 AllianceGenome:Xenbase:XB-GENE-17333490
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Summary
    Predicted to enable ATP binding activity; microtubule binding activity; and protein kinase activity. Predicted to act upstream of or within several processes, including axoneme assembly; generation of neurons; and protein phosphorylation. Predicted to be located in microtubule; microtubule organizing center; and neuron projection. Orthologous to human DCLK1 (doublecortin like kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See dclk1.S in Genome Data Viewer
    Location:
    chromosome: 2S
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (143953025..144174776)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (134940115..135165875)

    Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108709941 Neighboring gene coiled-coil domain containing 169 S homeolog Neighboring gene neurobeachin S homeolog Neighboring gene mab-21-like 1 S homeolog Neighboring gene StAR related lipid transfer domain containing 13 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within axoneme assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neuron migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neuron projection morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within retina development in camera-type eye IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein kinase DCLK1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      143953025..144174776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018250241.2 → XP_018105730.1  serine/threonine-protein kinase DCLK1 isoform X4

      UniProtKB/TrEMBL
      A0A8J0UE45
      Related
      ENSXLAP00005062462.1, ENSXLAT00005063915.1

    2. XM_018250240.2 → XP_018105729.1  serine/threonine-protein kinase DCLK1 isoform X1

      UniProtKB/TrEMBL
      A0A8J0UM50, A0A974HWV9
      Related
      ENSXLAP00005062475.1, ENSXLAT00005063928.1

    3. XM_041584499.1 → XP_041440433.1  serine/threonine-protein kinase DCLK1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MFX0, A0A974HWV9
      Related
      ENSXLAP00005062490.1, ENSXLAT00005063943.1
      Conserved Domains (3) summary
      cd17069
      Location:182 → 265
      DCX2; Dublecortin-like domain 2
      cd17140
      Location:55 → 143
      DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
      cl21453
      Location:383 → 650
      PKc_like; Protein Kinases, catalytic domain

    4. XM_041584500.1 → XP_041440434.1  serine/threonine-protein kinase DCLK1 isoform X3

      UniProtKB/TrEMBL
      A0A8J1MFD8
      Related
      ENSXLAP00005062432.1, ENSXLAT00005063885.1
      Conserved Domains (1) summary
      cd14095
      Location:82 → 339
      STKc_DCKL; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase (also called Doublecortin-like and CAM kinase-like)
    Nucleotide Protein Strain
    Heading Accession and Version

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